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  • Title: Response of psoriatic nails to oral photochemotherapy.
    Author: Marx JL, Scher RK.
    Journal: Arch Dermatol; 1980 Sep; 116(9):1023-24. PubMed ID: 7416754.
    Abstract:
    Ten patients with generalized psoriasis, which included nail involvement, were treated with total-body oral photochemotherapy. A combination of methoxsalen and high-intensity ultraviolet A radiation was employed and its therapeutic efficacy in nail psoriasis ascertained. Among the ten patients, there were 26 instances of the following nail signs: pitting, onycholysis, "oil drop" change, subungual hyperkeratosis, nail-plate crumbling, proximal nail-fold psoriasis, and onychorrhexis. Of the 26, eighteen improved by 50% or more. Only pitting failed to respond to therapy in all of the eight patients who had this change.
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