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  • Title: [Importance of the diagnosis of congenital developmental defects in the practice of pathologists].
    Author: Laziuk GI.
    Journal: Arkh Patol; 1980; 42(7):24-8. PubMed ID: 7417019.
    Abstract:
    Composite studies of 1286 stillborns and infants with congenital malformations (CMF) dying at the age under 1 year conducted in the Teratological Center of Minsk showed that in specialized therapeutic institutions the causes of CMF could be established in at least 70% of the cases. In the infant autopsy materials, 12% of CMF were associated with chromosome pathology, 17% with single gene mutations, over 40% had multifactor determinants and 2.7% were due to teratogenic effects.
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