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  • Title: Carbodiimides inhibit the acid-induced purple-to-blue transition of bacteriorhodopsin.
    Author: Renthal R, Wallace B.
    Journal: Biochim Biophys Acta; 1980 Oct 03; 592(3):621-5. PubMed ID: 7417419.
    Abstract:
    Reaction of purple membrane with water soluble carbodiimides inhibits the spectral transition from purple to blue observed at acid pH. The pK and Hill constant for this transition are shifted from 3.4 to 2.6 and from 1.8 to 0.85, respectively. The results suggest a connection between the uptake side of the proton pump and the purple-to-blue transition.
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