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  • Title: Electrophoretic analysis of specific proteins in the regenerating goldfish retinotectal pathway.
    Author: Quitschke W, Francis A, Schechter N.
    Journal: Brain Res; 1980 Nov 17; 201(2):347-60. PubMed ID: 7417846.
    Abstract:
    Proteins in the goldfish retinotectal pathway were analyzed by 2-D gel electrophoresis, under conditions of optic nerve crush or eye removal. A specific cluster of proteins was detected, consisting of 4 components, all of which are highly concentrated in the intact optic nerve. Two components were not detectable in non-visual areas of the goldfish brain. The total cluster was diminished by about 80% in the denervated optic tectum, and its level was restored during optic nerve regeneration. These data were interpreted as evidence for visual system-specific proteins in the goldfish retinotectal pathway.
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