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Title: P1 incompatibility in pigeon breeders. Author: Radermecker M, Bruwier M, Bury J, Fillet G. Journal: Clin Allergy; 1980 May; 10(3):309-12. PubMed ID: 7418188. Abstract: Pigeon breeders of the P2 blood phenotype may develop anti-P1 haemagglutinins as a consequence of natural immunization to pigeon dust. The half-life of labelled P1 erythrocytes was determined in two P2 pigeon breeders otherwise compatible except for the presence of anti-P1 antibodies and in four compatible controls without anti-P1. The half-life of tagged cells was within the normal range in one breeder but significantly reduced in the other, indicating that P1 incompatibility may occur in vivo. Since anti-P1 antibodies are found in about 20% of P2 pigeon breeders, it is suggested that this group may be prone to developing an incompatibility to transfused P1 red cells.[Abstract] [Full Text] [Related] [New Search]