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  • Title: The effect of cycloheximide and carbon tetrachloride in Ehrlich ascites tumour-bearing mice.
    Author: Parry EW.
    Journal: Gan; 1980 Jun; 71(3):275-9. PubMed ID: 7418971.
    Abstract:
    Treatment with cycloheximide and a hepatotoxic dose of CCl4 (well tolerated in normal animals) is acutely toxic in animals bearing the Ehrlich ascites tumour. Reduction in tumour load 4 hr after the administration of cycloheximide and CCl4 is life-saving: treatment with a hepatotoxic dose of CCl4 30 hr before challenge with cycloheximide and CCl4 also nullifies that otherwise life-threatening treatment.
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