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Title: Role of Clostridium difficile in a case of nonantibiotic-associated pseudomembranous colitis. Author: Peikin SR, Galdibini J, Bartlett JG. Journal: Gastroenterology; 1980 Nov; 79(5 Pt 1):948-51. PubMed ID: 7419019. Abstract: A 57-yr-old woman with chronic diarrhea, mild azotemia, and red cell casts in her urine was found to have pseudomembranous colitis. She had not received antimicrobial agents for at least 2 yr. Membranoproliferative glomerulonephritis was found in kidney biopsy, and her renal function improved spontaneously. Pseudomembranous colitis was diagnosed by endoscopic biopsy. Her stool contained a cytophatic toxin that was neutralized by Clostridium sordellii antitoxin, and Clostridium difficile was cultured on selective media. This case indicates that C. difficile may be a cause of nonantibiotic-associated pseudomembranous colitis, as well as antibiotic-associated pseudomembranous colitis.[Abstract] [Full Text] [Related] [New Search]