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  • Title: Comparison of the kinetic properties of troponin-C and dansylaziridine-labeled troponin-C1.
    Author: Iio T, Kondo H.
    Journal: J Biochem; 1980 Aug; 88(2):547-56. PubMed ID: 7419512.
    Abstract:
    Comparison of the kinetic properties of troponin-C and dansylaziridine-labeled troponin-C revealed that the calcium ion binding and removal reactions with the low affinity Ca2+-binding sites (sites I and II) and the resultant local conformational change are rapid processes, and that the calcium ion binding and removal reactions with the high affinity Ca2+-binding sites (sites III and IV) are also rapid, whereas the resultant local conformational change is a slow process. It is also shown in this work that the latter processes are independent of the former processes.
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