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  • Title: Urinary hydroxyproline excretion as a marker of osseous metastasis in carcinoma of the prostate.
    Author: Mooppan MM, Wax SH, Kim H, Wang JC, Tobin MS.
    Journal: J Urol; 1980 May; 123(5):694-6. PubMed ID: 7420557.
    Abstract:
    Urinary hydroxyproline was elevated significantly in patients with untreated stage D prostatic carcinoma when compared to values in patients with benign prostatic hypertrophy and prostatic carcinoma without bony metastasis. Our results indicate that hydroxyproline may be a valuable marker in early staging, followup and evaluating treatment in prostatic cancer.
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