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  • Title: [Degenerative and regenerative phenomena in pigmented rabbit irides following irradiation with the xenon arc lamp at different pulse energies (author's transl)].
    Author: Wechsler A, Portmann H, van der Zypen E, Fankhauser F.
    Journal: Klin Monbl Augenheilkd; 1980 Apr; 176(4):504-8. PubMed ID: 7421019.
    Abstract:
    The morphological condition of the pigmented rabbit iris following irradiation with a Xenon arclamp at four different pulse energies was analyzed. It was shown that: 1. There is a direct relationship between the applied pulse energy and the extent, as well as the rate, of secondary-degenerative transformations. 2. Secondary-degenerative and repair processes occur simultaneously. 3. As opposed to the primary damage event, secondary degeneration appears to progress from the back to the front of the iris. 4. As a rule, pulse energies of less than 1 Joule do not lead to secondary perforation of the iris. Fifteen weeks, after the damage event, regeneration of connective tissue and the larger blood vessels, as well as of myelinated and unmyelinated nerves may be found. 5. The inducing factors, as well as those sustaining the process of secondary degeneration after irradiation of the rabbit iris with high pulse energies, cannot be explained on the basis of morphological findings alone.
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