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  • Title: Induction of zinc-thionein in rat liver and kidneys by zinc loading as studied at isometallothionein levels.
    Author: Suzuki KT, Yamamura M.
    Journal: Toxicol Lett; 1980 Jun; 6(1):59-65. PubMed ID: 7423547.
    Abstract:
    Zinc acetate was injected i.p. into female rats to try to clarify the detailed induction and degradation pathways of zinc-thionein (Zn-th) at isometallothionein levels in liver and kidneys. Injected zinc in serum decreased with the induction of Zn-th in the liver and kidneys, and the amounts of Zn-th in both tissues attained maxima 24 h after injection. The relative ratios of isometallothioneins changed with time in both tissues. The changes are compared with those of cadmium (Cd) loading.
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