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Title: The effect of X-irradiation on the fertility and on the induction of meiotic chromosome rearrangements in mice and their first generation. Author: Savković N, Pecevski J, Marić N, Radivojević D. Journal: Strahlentherapie; 1980 Jun; 156(6):437-40. PubMed ID: 7423570. Abstract: The effect of whole-body or local irradiation with X-rays at a dose of 600 R on the induction of chromosomal translocations in the diakinesis metaphase I of the meiosis in treated and F1 males has been examined along with their fertility. Our results show the high percentage of mortality in whole-body irradiated mice. The percentage of the fertility was 25% in whole-body, and 93.7% in locally irradiated males. The testis weight was also reduced. The percentage of chromosomal translocations in diakinesis, metaphase I, or the meiosis was higher after whole-body irradiation than after local irradiation. In F1 males both types of irradiation induced chromosomal translocations.[Abstract] [Full Text] [Related] [New Search]