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  • Title: Metaproterenol and theophylline in asthmatic children.
    Author: Rachelefsky GS, Katz RM, Mickey MR, Siegel SC.
    Journal: Ann Allergy; 1980 Oct; 45(4):207-12. PubMed ID: 7425389.
    Abstract:
    Metaproterenol (M) and theophylline (T) were compared in an eight-week randomized, double-blind, crossover study in 20 moderately severe asthmatic children. All subjects were clinically maintained on both M and T. T was superior when evaluating cough, attacks, extra medicines, and PEFR values. Diary analysis revealed T better in 11, M in six and M/T equal in three subjects. Side effects were more common with T. M might be an adequate alternative to T in the treatment of asthmatic children requiring daily bronchodilators.
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