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  • Title: Biosynthesis of versicolorin A.
    Author: Anderson MS, Dutton MF.
    Journal: Appl Environ Microbiol; 1980 Oct; 40(4):706-9. PubMed ID: 7425622.
    Abstract:
    The incorporation of various potential intermediates into versicolorin A by a versicolorin A-accumulating mutant of Aspergillus parasiticus was studied. Both whole mycelium and cell-free extracts of this mutant were able to convert 14C-labeled versiconal hemiacetal acetate to versicolorin A. By the use of a labeled double substrate technique it was shown that two other compounds, versicolorin A hemiacetal and its acetate derivative, were also converted to versicolorin A. It is concluded that one or both of these compounds are intermediates in the biosynthesis of versicolorin A and therefore may possibly be involved in the biogenesis of the aflatoxins.
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