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  • Title: The congenital warfarin syndrome: a case report.
    Author: Baillie M, Allen ED, Elkington AR.
    Journal: Br J Ophthalmol; 1980 Aug; 64(8):633-5. PubMed ID: 7426582.
    Abstract:
    A case is reported of a baby born with congenital abnormalities due to maternal ingestion of warfarin during pregnancy. Warfarin is known to be teratogenic, producing characteristic abnormalities, namely a hypoplastic nose, stippled epiphyses, and skeletal abnormalities. A variety of ocular abnormalities have been reported. Ophthalmologists should seek a history of maternal warfarin ingestion when seeing a baby with congenital ocular abnormalities. They should also be aware of the possible teratogenic effects when considering warfarin therapy for a woman of childbearing age.
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