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  • Title: Oscillations in plasma cortisol levels of newborns during exchange transfusion.
    Author: Zoltán E, Sólyom J.
    Journal: Endokrinologie; 1980 Jun; 75(3):335-40. PubMed ID: 7428711.
    Abstract:
    Plasma cortisol concentration was determined in blood samples obtained in six newborns during exchange transfusion at 3--5 minute intervals. A radiotransin-assay using horse serum as a binding protein and toluene-based scintillation fluid for separation of unbound tracer proved to be a relatively specific method for determination of cortisol level in the plasma of newborns. Irregular oscillations were observed in four newborns, whereas a single peak could be demonstrated in two cases during the 40--70 minute period observed. The results suggest that the CRF-ACTH-cortisol secretion may already be episodic in the newborn period.
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