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  • Title: Chronic hemofiltration. A critical evaluation of a new method for the treatment of blood.
    Author: Schaefer K, von Herrath D, Gullberg CA, Asmus G, Hüfler M, Offermann G, Cremer H, Heuck CC, Ritz E.
    Journal: Artif Organs; 1978 Nov; 2(4):386-94. PubMed ID: 743012.
    Abstract:
    The experiences which have been compiled in more than 2400 hemofiltrations confirm that this method represents an alternative way of treating uremic patients. The main advantages of chronic hemofiltration are the comfort of the patient and the ease in handling excess overhydration without extending treatment time, which is less than 3 X 3 hours/week if adequate hemofilters are used. With regard to the improvement of such typical uremic complications as severe hypertension, hypertriglyceridemia or neuropathy, hemofiltration does not seem to be superior to hemodialysis. However, since most hemofiltration patients do not require phosphate binders and, additionally, remarkable amounts of parathyroid hormone are removed during one hemofiltration, it appears possible that hemofiltration might be an important therapeutic alternative for those renal patients who suffer from severe hyperphosphatemia and secondary hyperparathyroidism.
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