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  • Title: Biologic gastric emptying time in diabetic patients, using Tc-99m-labeled resin-oatmeal with and without metoclopramide.
    Author: Domstad PA, Kim EE, Coupal JJ, Beihn R, Yonts S, Choy YC, Mandelstam P, DeLand FH.
    Journal: J Nucl Med; 1980 Nov; 21(11):1098-100. PubMed ID: 7431111.
    Abstract:
    Biologic gastric emptying time (BGET) was measured in 24 patients with severe diabetes mellitus complicated by vascular damage and peripheral or sensory neuropathy. This population had a BGET of 192 +/- 32.9 min (mean +/- s.e.m. normal 40-85 min). Patients with diabetic gastroenteropathy had prolongation of BGET to 295 +/- 45 (p < 0.05). Metoclopramide significantly shortened BGET in this subgroup to 101 +/- 40 min, with return to normal values in eight of the 12 patients given the drug. The Tc-99m-labeled resin-oatmeal test meal used as described in this study provides a reliable measure of BGET and of the response to metoclopramide.
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