These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Changes in luminal plasma and disappearance of spermatozoa from the ligated cauda epididymidis of the androgen-deficient rabbit.
    Author: Jones R, Dott HM.
    Journal: J Reprod Fertil; 1980 Sep; 60(1):65-72. PubMed ID: 7431330.
    Abstract:
    By 3 weeks after castration the majority of spermatozoa in the ligated cauda epididymidis were dead and decapitated and there was a 46% reduction in the total number of spermatozoa. By 5 weeks after castration > 99% of spermatozoa had disappeared. Electrophoresis of cauda epididymal plasma (CEP) on polyacrylamide gels revealed that after castration the protein composition of CEP changed from a pattern specific to the epididymis to one similar to blood serum. These changes in the luminal content could be prevented by administering testosterone. When spermatoza from the cauda epididymidis were diluted in CEP from normal rabbits they remained motile for several hours at room temperature. Dilution in CEP from 3- ro 5-week castrated animals stimulated vigorous forward motility but this declined to very low levels after 40 min. The evidence indicates that dead spermatozoa can be removed from the epididymis after castration by mechanisms not involving granuloma formation.
    [Abstract] [Full Text] [Related] [New Search]