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Title: Rupture of the uterus after midtrimester prostaglandin abortion. Author: Cederqvist LL, Birnbaum SJ. Journal: J Reprod Med; 1980 Sep; 25(3):136-8. PubMed ID: 7431358. Abstract: A case is reported of rupture of the uterus after intraamniotic injection of prostaglandin F2 alpha followed by intravenous oxytocin. The literature is reviewed and the management discussed. A 34-year old Puerto Rican woman gravida 8, para 5, abortions 1, miscarriage 1, living children 4 admitted to the New York Hospital-Cornell Medical Center for prostaglandin abortion had a delayed diagnosis of rupture of the left uterine artery. The delay in diagnosis was attributed to the intraligamentous and retroperitoneal location of the hematoma. The bleeding was controlled by performing a supracervical hysterectomy and ligation of the left hypogastric artery. The patient recovered uneventfully. Rupture of the uterus is a less common occurence than cervical lacerations, which occur in 1% to 2% of 2nd trimester abortions and most frequently among young primigravidas. Uterine rupture occurs mostly in multiparous women and does not appear to be prevented by laminaria tents. Uterine rupture at term following oxytocin induction has been related with multiparous patients. Uterine rupture has also ben observed following induction of midtrimester abortion with intraamniotic hypertonic saline or prostaglandin analogs, and the dilatation and evacuation method. Of 12 documented cases of uterine ruptures after saline/prostaglandin-induced abortion, 11 necessitated hysterectomy and 2 patients died from blood loss. Management of oxytocin and prostaglandin-induced abortion is briefly discussed.[Abstract] [Full Text] [Related] [New Search]