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  • Title: Calcific stenosis of a glutaraldehyde-treated porcine bioprosthesis in the aortic position.
    Author: Gordon MH, Walters MB, Allen P, Burton JD.
    Journal: J Thorac Cardiovasc Surg; 1980 Nov; 80(5):788-91. PubMed ID: 7431977.
    Abstract:
    The porcine xenograft bioprosthesis is used widely at the present time, although its long-term durability is still being evaluated. Calcification resulting in stenosis of the glutaraldehyde-treated bioprosthesis has been reported infrequently. In the patient described herein, severe calcific stenosis of a porcine xenograft in the aortic position occurred 45 months after implantation. This report emphasizes the life-threatening and rapidly progressive nature of this complication in the long-term survivor after valve replacement.
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