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  • Title: Effects of danazol and lynestrenol on serum lipoproteins in endometriosis.
    Author: Mälkönen M, Manninen V, Hirvonen E.
    Journal: Clin Pharmacol Ther; 1980 Nov; 28(5):602-4. PubMed ID: 7438678.
    Abstract:
    The treatment of endometriosis with danazol or lynestrenol decreased cholesterol content of plasma high-density lipoproteins by 50% and 32%. There were simultaneous increases in low-density lipoprotein cholesterol content of 51% and 19%. We suggest that changes induced by lynestrenol are due to progestational activity, while in the case of danazol both antigonadotropic and androgenic activities are involved.
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