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  • Title: [Pharmacological activity of the optical isomers of sydnocarb].
    Author: Al'tshuler RA, Mashkovskiĭ MD.
    Journal: Farmakol Toksikol; 1980; 43(4):345-9. PubMed ID: 7439363.
    Abstract:
    Of the two optical isomers of sydnocarb, only 1- (or 1R)-isomer exerts a stimulant effect on the central nervous system. By its stimulant action it differs from both optical isomers of amphetamine. The activity of 1-(IR)-sydnocarb as measured by the locomotor excitation test is similar to that of d(1S)-amphetamine but is significantly less powerful as indicated by stereotypy, hyperthermia, anorexigenic action and antagonism to the depressant effects of reserpine.
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