These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Stimulation of the secondary anticlotting system by DFP-alpha-thrombin].
    Author: Kudriashov BA, Umarova BA, Strukova SM, Liapina LA.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1980 Oct; 66(10):1460-5. PubMed ID: 7439438.
    Abstract:
    Inhibition of the alpha--thrombin DFP catalytic portion does not incapacitate it physiologically: i. v. administration of such thrombin stimulates the second anticoagulating system. Aminasin abolishes this effect. These findings suggest that the thrombin preserves the portion of molecule responsible for reflex stimulation of the anticoagulating system. Microstructural changes of the apolar portion in different conditions deprives the alpha--thrombin to its ability to interact with the vascular bed's chemoreceptors. I. v. administration of such thrombin evoked no defense response in the organism.
    [Abstract] [Full Text] [Related] [New Search]