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  • Title: Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ARA-C.
    Author: Hromas RA, Markel DE, Scholes VE.
    Journal: Res Commun Chem Pathol Pharmacol; 1980 Nov; 30(2):365-8. PubMed ID: 7444164.
    Abstract:
    Mouse L1210 leukemia cells killed by ara-C, an anti-tumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was shown to be dose dependent. At higher concentrations of ara-C cells died earlier in the S phase.
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