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  • Title: Prophylactic treatment of alcoholism by lithium carbonate. A controlled study.
    Author: Merry J, Reynolds CM, Bailey J, Coppen A.
    Journal: Lancet; 1976 Sep 04; 1(7984):481-2. PubMed ID: 74457.
    Abstract:
    Lithium therapy has been shown to have a therapeutic influence in reducing the drinking and incapacity by alcohol in depressive alcoholics in a prospective double-blind placebo-controlled trial conducted over one year, but it had no significant effect on non-depressed patients. Patients in the trial treated by placebo had significantly greater alcoholic morbidity if they were depressive than if they were non-depressive.
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