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  • Title: [Role of the mesencephalon reticular formation in the effect of ethosuximide on a cortical epileptogenic focus].
    Author: Kästner I, Mestwirischwili LP, Bagaschwili TU.
    Journal: Acta Biol Med Ger; 1980; 39(4):455-9. PubMed ID: 7445895.
    Abstract:
    Ethosuximide provoked in encéphale isolé cats a dose-dependent suppression or facilitation of strychnine focus spiking activity, and in combination with high frequency stimulation of formatio reticularis mesencephali a significant activation of the cortical focus. The results seem to show that the influence of ethosuximide on the formatio reticularis mesencephali is one--if not the main--component of the drug effect.
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