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  • Title: Rimantadine hydrochloride blocks the second step of influenza virus uncoating.
    Author: Bukrinskaya AG, Vorkunova NK, Narmanbetova RA.
    Journal: Arch Virol; 1980; 66(3):275-82. PubMed ID: 7447705.
    Abstract:
    Two steps of influenza virus A/WSN uncoating in MDCK cells are described. The products of the first step are cores which accumulate in the nuclear-associated cytoplasm. The products of the second step are ribonucleoproteins which penetrate the nuclei. Rimantadine blocks the second step without interfering with the first one.
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