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  • Title: [Effect of pH on the properties of planar lipid bilayers of cholesterol and alpha-monolaurine].
    Author: Bagaveev IA, Rovin IuG, Nedozorov PM, Likhatskaia GN.
    Journal: Biofizika; 1980; 25(6):1091-2. PubMed ID: 7448225.
    Abstract:
    It is discovered that pH of liquid electrolyte influences the structure, stability and conductance of bilayer lipid membranes (BLM) formed from cholesterol-alpha-monolaurine mixture in n-octane. The most stable BLM are formed at cholesterol-alpha-monolaurine weight ratio 1:1, BLM specific resistance being maximal and their thickness minimal (2.9 nm). A sharp reduction of BLM stability is noted when pH is deviated in acidic or alkaline medium. The obtained data are discussed from the viewpoint of adsorbed charge influence on the structure of BLM formed of uncharged lipids.
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