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  • Title: [Body's reaction to controlled hypercapnia during muscular exercise].
    Author: Breslav IS, Shmeleva AM, Sidikov SM.
    Journal: Biull Eksp Biol Med; 1980 Nov; 90(11):523-5. PubMed ID: 7448383.
    Abstract:
    The respiratory response to the monitored alveolar hypercapnia was studied in normal young men at rest and minute 5 after graded muscular exercise. The exercise did not produce consistent changes in the slope of the regression line that reflected the growth of pulmonary ventilation by 1 mm Hg, pCO2 and therefore did not change the sensitivity of the respiration control apparatus to hypercapnia. At the same time this line moved to the left proportionally to the degree of the exercise as a result of the displacement of the point crossing with the "zero" ventilation axis towards less values of pCO3. In consequence any given magnitude of hypercapnia during the exercise corresponded with a higher ventilation rate as compared to that at rest. Thus, in the course of stable period of muscular exercise the respiration regulation involved an additional stimulus that interacted with hypercapnia according to the additive type.
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