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  • Title: [The antimycotic activity of acyl derivaties of 2-oximino-1,3-benzodithiol].
    Author: Pavanetto F, Mazza M, Montanari L, Modena T.
    Journal: Farmaco Sci; 1980 Sep; 35(9):791-5. PubMed ID: 7450059.
    Abstract:
    A series of esters of 2-oximino-1,3-benzodithiol [substances (II leads to XV)] was prepared and tested for antifungal activity in vitro. The substances were obtained by condensation of 2-oximino-1,3-benzodithiol with suitable acylation agents. The fungistatic activity of the products was tested in vitro against the four strains: Candida albicans, Candida tropicalis, Saccharomyces cerevisiae and Trichophyton mentagrophytes. The results reported in the Table I show the interesting antimycotic activity observed for 2-oximino-1,3-benzodithiol, which is apparently connected with the presence of a free oximino group.
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