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  • Title: Increased erythrocytic spermine in Duchenne muscular dystrophy.
    Author: Mollica F, Li Volti S, Rapisarda A, Longo G, Pavone L, Vanella A.
    Journal: Pediatr Res; 1980 Nov; 14(11):1196-8. PubMed ID: 7454431.
    Abstract:
    Erythrocytes of patients with Duchenne muscular dystrophy have been found to have elevated levels of spermine, a polyamine with a membrane-stabilizing action. Although a specific, increased spermine concentration is an additional biochemical abnormality documenting the involvement of erythrocyte membrane in Duchenne muscular dystrophy. Normal level of spermine were found in female carriers.
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