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  • Title: Allergy to penicillin. Comparison of "in vivo" and "in vitro" tests.
    Author: Olivé A, Huguet J, Vich JM, García-Calderón JV, García-Calderón PA.
    Journal: Allergol Immunopathol (Madr); 1980; 8(2):105-10. PubMed ID: 7457286.
    Abstract:
    Skin tests (SKT) and Lymphocyte Transformation Test (LTT) utilizing sodium penicillin G (PNG) and penicilloyl polylysine (PPL) and Rast to penicilloyl G were carried out on forty patients with a history of allergic reactions to penicillin, the results obtained indicated no statistically significant difference between the use of SKT or LTT in the diagnosis of allergy to penicillin (X2, p > 0,05), while the use of Rast showed a statistically significant difference (X2, p < 0,001) in favour of LTT and SKT. The use of either type of allergen (PNG or PPL) in LTT or SKT showed a significant difference in favour of the former (X2, p < 0,01).
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