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  • Title: [Role of the mastocytes during functional activation of the thyroid].
    Author: Balboni GC, Catini C, Gheri G.
    Journal: Bull Assoc Anat (Nancy); 1980 Mar; 64(184):55-8. PubMed ID: 7459439.
    Abstract:
    The behaviour of biogenic amines in mastocytes has been studied in the thyroid glands of rats treated with 2 U.I. of TSH. The histochemical evaluation of histamine and 5-HT in mastocytes with the method of fluorochromization has been carried out at 20 minutes and 120 minutes after TSH administration. After 20 minutes, the thyroid glands do not present evident parenchymal changes, but the positivity for biogenic amines in mastocytes decreases in comparison to the controls, while this positivity begins to be evident in the interstitial tissue. After 120 minutes, the thyroid gland shows a microfollicular arrangement and the fluorescent biogenic amines appear to be released in the interstitium by degranulating mastocytes, nearly entirely negative to fluorochromization.
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