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  • Title: [Enzymes of carbohydrate and lipid metabolism in dependence on age (author's transl)].
    Author: Richter V, Rassoul F.
    Journal: Z Alternsforsch; 1978; 33(6):487-91. PubMed ID: 746664.
    Abstract:
    The levels of the rat liver enzymes glucose-6-phosphate-dehydrogenase, alpha-glycerophosphate-dehydrogenase and citrate cleavage enzyme decrease between the age groups of 3 and 18 months. The half-life time of these enzymes is uneffected by age and the diminished levels of the enzymes in the liver of old rats can be ascribed to a reduced rate of enzyme synthesis. The half-life time of malic enzyme decreases as a function of age and this increased enzyme destruction may contribute to the diminished malic enzyme level of old rat liver.
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