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  • Title: Localization of a vasoactive intestinal peptide-producing tumor with selective venous sampling.
    Author: Smith FR, Rogers AI.
    Journal: Am J Gastroenterol; 1980 Sep; 74(3):282-4. PubMed ID: 7468568.
    Abstract:
    A case of vasoactive intestinal peptide-producing adenoma of the tail of the pancreas (VIP) successfully managed by surgical resection is presented. Peripheral venous VIP levels correlated with the severity of the diarrhea. Intraoperatively, the VIP levels in the splenic and portal veins were 485 and 100 pg./ml., respectively. These data suggest that preoperative selective transhepatic venous catheterization for VIP sampling might be used to establish the site of VIP production and, thereby, direct surgical management. This technic requires further evaluation regarding its role in this clinical setting.
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