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  • Title: [Effect of antibacterial preparations on carbohydrate hydrolysis and absorption in the small intestine].
    Author: Ishchuk IS, Andreĭchin MA.
    Journal: Antibiotiki; 1980 Dec; 25(12):932-5. PubMed ID: 7469399.
    Abstract:
    The effect of levomycetin, phthalysulfathiazol, furazolidone and enteroseptal on hydrolysis and absorption of carbohydrates in the thin intestine of rabbits was studied. The level of sugar assimilation was estimated by the glycemia curves after differential loads with lactose, maltose, sucrose, glucose and galactose combination with glucose. The repressive effects of the chemotherapeutic drugs on both the parietal digestion of disaccharides and the adsorption of their monosaccharides was shown. Chloramphenicol lylsulfathiazol inhibited maltose hydrolysis, glucose adsorption and stimulated hydrolysis of lactose an absorption of its derivatives. Furazolidon and enteroseptal inhibited only lactose assimilation. The effect of the drugs on the intestine hydrolysis and absorption of the sugars depended to a significant extent on the individual host reaction.
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