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Title: A possible role of rabbit heart cytosol tocopherol binding in the transfer of tocopherol into nuclei. Author: Guarnieri C, Flamigni F, Caldarera CM. Journal: Biochem J; 1980 Aug 15; 190(2):469-71. PubMed ID: 7470061. Abstract: An alpha-tocopherol-binding macromolecule was isolated from the heart cytosol of rabbits fed for 1 month with an alpha-tocopherol-deficient diet. The amount of [3H]-tocopherol bound to nuclear chromatin was increased when the alpha-tocopherol-deficient heart nuclei were incubated in the presence of [3H]tocopherol-cytosol complex. In this condition, large amounts of [3H]tocopherol were associated with a subnuclear fraction that contained non-histone acidic proteins.[Abstract] [Full Text] [Related] [New Search]