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  • Title: Cure of prophage in Staphylococcus aureus by furocoumarin photoadditions.
    Author: Cavalcanti SM, Siqueira Júnior JP.
    Journal: Microbios; 1995; 81(327):85-91. PubMed ID: 7476557.
    Abstract:
    In a previous report curing of prophage in Staphylococcus aureus by treatment with 8-methoxypsoralen plus near-UV (365 nm) radiation was described. In the present work the use of angelicin and 4,5',8-trimethylpsoralen and repeated irradiation show that monoadducts and DNA interstrand cross-links formed by furocoumarin photoaddition are involved in the curing of the prophage responsible for the suppression of the lipolytic activity in a putative repair proficient strain of Staphylococcus aureus.
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