These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Catabolite modification of acid tolerance of Streptococcus mutans GS-5.
    Author: Belli WA, Marquis RE.
    Journal: Oral Microbiol Immunol; 1994 Feb; 9(1):29-34. PubMed ID: 7478752.
    Abstract:
    The acid tolerance of Streptococcus mutans GS-5 in standard pH-drop assays was found to be affected by the sugar used in the assay and also by the sugar used for growth of the organism. For example, acid tolerance was lower when galactose was used as catabolite than when glucose was used, apparently because galactose/proton symport brought protons extruded by the F-ATPase back into the cell and thus reduced delta pH across the cell membrane. The acid tolerance of glycolysis was related directly to the capacities of the cells to produce acid glycolytically, or probably more correctly, to their capacities to produce adenosine triphosphate but not to acid tolerance of phosphotransferase systems for sugar uptake. Thus, glycolytic acid tolerance of S. mutans depends not only on environmental factors such as potassium or magnesium levels but also on the specific catabolites the organism is metabolizing or to which it has become metabolically adapted.
    [Abstract] [Full Text] [Related] [New Search]