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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Initial clinical experience with a new dual sensor SSIR pacemaker controlled by body activity and minute ventilation.
    Author: Alt E, Combs W, Fotuhi P, Bambl E, Wahlstrand J, Willhaus R.
    Journal: Pacing Clin Electrophysiol; 1995 Aug; 18(8):1487-95. PubMed ID: 7479170.
    Abstract:
    Fourteen patients were implanted with a single chamber dual sensor pacemaker (Legend Plus) that measures minute ventilation (VE) via variations in impedance between a bipolar lead and the pacemaker case, and activity via a piezoelectric crystal bonded to the pacemaker case. Chronotropic incompetent patients were exercised on a treadmill and a bicycle in dual sensor mode. Activity only indicated pacing rate was measured using a strap-on pacemaker. Both implanted and strap-on pacemakers were adjusted to yield a steady-state pacing rate of 100 beats/min during hall walk. Pacing rate, VE, and oxygen uptake (VO2) were measured continuously. Linear curve fit analysis slopes for plots of VE versus pacing rate during exercise (1.33-1.49) compared favorably to values reported in normals. Peak pacing rates achieved for treadmill and bicycle testing for dual sensor mode were higher than activity mode alone. Slopes of heart rate to VE or VO2 were not significantly different (P < 0.05) for dual sensor mode in contrast to activity alone. In conclusion, the Legend Plus dual sensor rate adaptive pacing therapy delivered pacing rates more proportional to VE and VO2 under different types of exercise than rates indicated by a strap-on pacemaker in activity mode.
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