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  • Title: [The treatment of nephrotic-type chronic glomerulonephritis with Sandimmun (cyclosporin A)].
    Author: Mukhin NA, Tareeva IE, Krasnova TN, Shilov EM, Miroshnichenko NG.
    Journal: Ter Arkh; 1995; 67(8):13-5. PubMed ID: 7482320.
    Abstract:
    Sandimmun (ciclosporin A) treatment of chronic glomerulonephritis with nephrotic syndrome in a dose 2.5-5 mg/kg for 6-10 months relieved nephrotic syndrome in 2 and resulted in clinical improvement in other 2 of 4 patients treated. In 3 cases the patients failed previous therapy with high-dose corticosteroids and cytostatics. The drug reduced proteinuria, elevated serum levels of albumin and total protein, had low nephrotoxicity.
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