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  • Title: [The mechanisms of the cytoprotective action of prostacyclin in acute postoperative parotitis].
    Author: Dolgov SN, Filipenko PS.
    Journal: Stomatologiia (Mosk); 1995; 74(2):46-7. PubMed ID: 7482609.
    Abstract:
    Effects of prostaglandin I2 of the content of lipid peroxidation products and the activity of glutathione antioxidative system were studied in 60 dogs in whom acute nonepidemic parotitis was induced. Prostaglandin I2 was found to enhance the reactions of protective inhibition of metabolism with reduction of peroxidation level and activation of the antioxidative system, this permitting the cell to preserve its structural intactness. A conclusion is made about the possibility of using prostaglandin I2 for the prevention and therapy of acute nonepidemic parotitis.
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