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  • Title: [Diagnosis and therapy of autoimmune hepatitis].
    Author: Heintges T, Mohr L, Niederau C, Strohmeyer G.
    Journal: Z Gastroenterol; 1995 Aug; 33(8):462-7. PubMed ID: 7483741.
    Abstract:
    Thorough differential diagnosis in patients with autoimmune hepatitis is important since other liver disorders need different treatment regimen. Elevated transaminases and gamma-globulines and autoantibodies should make one think of autoimmune hepatitis. Liver biopsy is helpful but usually not a definitive proof of the diagnosis. Immunosuppressive therapy has to be administered for years and possibly leads to serious side effects. Therapy should only be discontinued if a complete remission is induced. Relapses after cessation of medical treatment occur frequently. If no remission is achieved lifelong immunosuppressive therapy has to be given. In decompensated disease liver transplantation offers a treatment with good prognosis.
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