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  • Title: Cardiopulmonary manifestations of systemic lupus erythematosus.
    Author: Collins RL, Turner RA, Nomeir AM, Hunt R, Johnson AM, McLean RL, Watts LE.
    Journal: J Rheumatol; 1978; 5(3):299-306. PubMed ID: 748554.
    Abstract:
    Nine of 17 patients (52%) with systemic lupus erythematosus participating in a controlled prospective study were found to have maximal mid-expiratory flow rates suggestive of obstructive or obstructive and restrictive pulmonary disease. Cigarette smokers with systemic lupus erythematosus had significantly lower (P less than .05) maximal mid-expiratory flow rates than either non-smokers with systemic lupus erythematosus or smokers with degenerative joint disease. By echocardiography, pericardial thickening was seen in six of 17 patients (41%) and mitral valvular abnormalities were noted in four of 17 (24%) patients with systemic lupus erythematosus. Echocardiography was found to be an effective means of detecting pericardial disease in patients with systemic lupus erythematosus.
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