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  • Title: Impairments of glycogen and drug metabolisms by chloropeptide, a hepatotoxic mycotoxin of Penicillium islandicum sopp.
    Author: Ueno Y, Ito T, Ueno I.
    Journal: J Toxicol Sci; 1978 Feb; 3(1):11-24. PubMed ID: 748561.
    Abstract:
    Administration of chloropeptide, a hepatotoxic cyclic pentapeptide of Penicillium islandicum Sopp, caused a marked decline in the hepatic glycogen synthetase activity with concomitant increase in NADP-dependent G-6-P dehydrogenase activity. The microsomalmixed function oxygenases were also reduced in the liver of rats following chloropeptide treatment.
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