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  • Title: Arachidonic acid in amniotic fluid after extra-amniotic instillation of rivanol for midtrimester abortion.
    Author: Olund A, Lunell NO.
    Journal: Prostaglandins; 1978 Dec; 16(6):989-94. PubMed ID: 748986.
    Abstract:
    Free arachidonic acid was measured by gas liquid chromatography in amniotic fluid in 13 women during induction of midtrimester abortion. The abortions were induced by extraamniotic instillation of 0.1% Rivanol. Serial sampling of amniotic fluid were performed through a transabdominal catheter up to 22 hrs. Free, total arachidonic acid showed a significant increase from 26 +/- 8 ng/ml to 293 +/- 102 ng/ml at 22 hrs. The percentage of free arachidonic acid in total free fatty acids increased significantly from 2.2 +/- 0.5 to 6.1 +/- 1.6+ during the same time. The results suggest a selective release of arachidonic acid during Rivanol-induced abortion.
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