These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Structure-activity relationship of pamamycins: effects of alkyl substituents.
    Author: Natsume M, Tazawa J, Yagi K, Abe H, Kondo S, Marumo S.
    Journal: J Antibiot (Tokyo); 1995 Oct; 48(10):1159-64. PubMed ID: 7490225.
    Abstract:
    Nine new pamamycin homologues were isolated from the culture broth of Streptomyces alboniger IFO 12738 using a combination of ODS and NH2 HPLCs, and their structures determined by GC-MS. The structural differences in these homologues are in the numbers and positions of methyl and ethyl groups. The aerial mycelium-inducing and growth-inhibitory activities in S. alboniger of these homologues and their antibiotic activity against Bacillus subtilis were examined. The effects of the alkyl substituents on these activities are discussed.
    [Abstract] [Full Text] [Related] [New Search]