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  • Title: [Thorotrast kidney as a precancerous condition].
    Author: Beckmann C, Reutter F, Gloor F.
    Journal: Schweiz Med Wochenschr; 1978 Dec 09; 108(49):1991-3. PubMed ID: 749198.
    Abstract:
    9 cases of "thorotrast kidney" after retrograde pyelography with reflux are presented. In 6 patients carcinoma of the renal pelvis developed 47--31 years after thorotrast pyelography. Because of this high rate of carcinoma induction, thorotrast kidney must be classified as a precancerous condition with high-rate tumor manifestation. Thorotrast kidney is diagnosed on X-ray by very opaque linear densities following the calices and pyelon. Early ureteronephrectomy is the treatment of choice in unilateral thorotrast kidneys. If uretero-nephrectomy is not possible, the patient should be followed up regularly with urinary cytologic examinations for early detection of malignancy.
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