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  • Title: [Acute myeloid leukemia (promyelocytic leukemia) with detection of virus particles in a boar. Histologic, histochemical and ultrastructural findings].
    Author: Breuer W, Heinritzi K, Hermanns W.
    Journal: Berl Munch Tierarztl Wochenschr; 1995 Oct; 108(10):380-4. PubMed ID: 7495410.
    Abstract:
    Acute myeloid leukemia is a rare finding in swine. A case of acute promyelocytic leukemia is described by light microscopy, enzyme- and immunohistochemistry as well as electron microscopy. Tumour cells can be demonstrated in bone marrow, lymph nodes, liver, spleen, kidneys, small intestine and myocardium. The tumorous neutrophil precursor cells are positive for naphthol-AS-D-chloroacetate esterase and lysozyme. They show ultrastructurally numerous granules as typical for promyelocytes. Virus particles of the oncorna-c-type can be demonstrated within the tumour cells.
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